Our lab is located at the Laboratoire de Physique Statistique building of the Ecole Normale Supérieure de Paris. Our research currently revolves around lipid storage and utilization mechanisms in cells, by using biophysical approaches based on droplet microfluidics and physical chemistry.
We especially study the formation of cellular lipid droplets, organelles at the core of cellular metabolism, and the specific binding of proteins to their surface. We combine for that in vitro emulsion approaches and cell biology
We use microfluidics to develop high throughput techniques to screen for the activity of membrane-bound proteins.
Lipid Droplets Can Spontaneously Bud Off from a Symmetric Bilayer
Our team has identified a key mechanism of cellular lipid droplet formation