2019
Membrane asymmetry imposes directionality on Lipid Droplet Emergence from the ER.
A Chorlay, L Monticelli, J Ferreira, KB M’barek, D Ajjaji, S Wang, E Johnson, M Omrane, R Beck, M Beller, P Carvalho, AR Thiam*, Developmental Cell
Seipin Facilitates Triglyceride Flow to Lipid Droplet and Counteracts Droplet Ripening via Endoplasmic Reticulum Contact.
VT Salo, S Li, H Vihinen, M Hölttä-Vuori, A Szkalisity, P Horvath, I Belevich, J Peränen, C Thiele, P Somerharju, H Zhao, A Santinho, AR Thiam*, E Jokitalo*, E Ikonen*, Developmental Cell
Dual binding motifs underpin the competitive targeting of perilipins1-3 to lipid droplets.
D Ajjaji, K Ben Mbarek, M Mimmack, C England, H Herscovitz, L Dong, S Patel, VSaudek, D; Small*, DB. Savage* and AR Thiam*, Molecular Biology of the Cell
Septin 9 has Two Polybasic Domains Critical to Septin Filament Assembly and Golgi Integrity
M Omrane, AS Camara, C Taveneau, N Benzoubir, T Tubiana, J Yu, R Guérois, D Samuel, B Goud, C Poüs, S Bressanelli, RC Garratt, AR Thiam*, A Gassama-Diagne*, iScience
Dual binding motifs underpin the hierarchical association of perilipins1-3 with lipid droplets.
D Ajjaji, K Ben Mbarek, M Mimmack, C England, H Herscovitz, L Dong, RG Kay, S Patel, V Saudek, DM Small, DB Savage, AR Thiam, Molecular Biology of the Cell
2018
An Asymmetry in Monolayer Tension Regulates Lipid Droplet Budding Direction
A. Chorlay, AR Thiam, Biophysical Journal
2017
Targeting of the Drosophila protein CG2254/Ldsdh1 to a subset of lipid droplets
ER Membrane Phospholipids and Surface Tension Control Cellular Lipid Droplet Formation
K. Ben M’barek, D. Ajjaji, A. Chorlay, S. Vanni, L. Forêt, AR Thiam. Developmental Cell
Lipid droplets can spontaneously bud off from a symmetrical bilayer
F. Deslandes, AR Thiam* and L. Forêt*. Biophysical Journal
The why, when and how of lipid droplet diversity
AR Thiam, M.Beller, Journal of Cell Science
2016
Seipin is required for converting nascent to mature lipid droplets
H. Wang, M. Becuwe, BE. Housden, C. Chitraju, AJ. Porras, MM. Graham, XN Liu, AR Thiam, DB. Savage, AK. Agarwal, A. Garg, MJ. Olarte, Q. Lin, F. Fröhlich, HK. Hannibal-Bach, S. Upadhyayula, N. Perrimon, T. Kirchhausen, CS. Ejsing, TC. Walther, RV. Farese Jr. eLife
The Physics of Lipid Droplet Nucleation, Growth and Budding.
AR Thiam, L. Forêt. BBA-Molecular and Cell Biology of Lipids
Conserved amphipathic helices mediate lipid droplet targeting of perilipins 1-3.
ER. Rowe, ML. Mimmack, AD. Barbosa, A. Haider, I. Isaac, MM. Ouberai, AR Thiam, S. Patel, V. Saudek, S. Siniossoglou, D.B. Savage. Journal of Biological Chemistry
2015
The Energy of COPI for Budding Membranes.
AR Thiam, F. Pincet. Plos One
Protein Crowding Is a Determinant of Lipid Droplet Protein Composition.
N. Kory, AR Thiam, RV Farese, Jr. and TC Walther. *Equal contribution – Developmental Cell
The stability of C12Ej bilayers probed with adhesive droplets.
K. Astafyeva, W. Urbach, N. Garroum, N. Taulier, AR Thiam. Langmuir
2008-2014
Single-step microfluidic fabrication of soft monodisperse polyelectrolyte microcapsules by interfacial complexation.
G. Kaufman, R. Boltyanskiy, S. Nejati, AR Thiam, M. Loewenberg, E. R. Dufresne, C. O. Osuji. Lab on a Chip
Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting.
F Wilfling*, AR Thiam*, MJ Olarte , J Wang , R Beck , TJ Gould , ES Allgeyer , F Pincet , J Bewersdorf , RV Farese, Jr. and TC Walther. *Equal contribution- eLife
The biophysics and cell biology of lipid droplets.
AR. Thiam, RV Farese Jr, TC Walther – Nature Reviews Molecular Cell Biology
COPI buds 60-nm lipid droplets from reconstituted water–phospholipid–triacylglyceride interfaces, suggesting a tension clamp function.
AR. Thiam, B Antonny, J Wang, J Delacotte, F Wilfling, TC Walther, R Beck, JE Rothman, and F Pincet – PNAS
From stability to permeability of adhesive emulsion bilayers.
AR. Thiam, N Bremond, J Bibette – Langmuir
Adhesive emulsion bilayers under an electric field: from unzipping to fusion.
AR. Thiam, N Bremond, J Bibette – Physical review letters
Breaking of an emulsion under an ac electric field.
AR. Thiam, N Bremond, J Bibette – Physical review letters
Decompressing emulsion droplets favors coalescence.
N Bremond, AR. Thiam, J Bibette – Physical review letters
Highlighted in Physical Review Focus: To merge drops must separate
Book Chapters
…soon
Lipids in dermal applications
Emulsions adhésives et non adhésives étudiées par la Microfluidique
Editor: Editions Universitaires Européennes
